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Through recording DNA profiles, scientists may find out the interactions between the genetic environment and occurrence of certain diseases (such as cardiovascular disease or cancer), and thus finding some new drugs or effective treatments in controlling these diseases.
It is often collaborated with the National Health Service.
The first national DNA database in the United Kingdom was established in April 1995, called National DNA Database (NDNAD).
By 2006, it contained 2.7 million DNA profiles (about 5.2% of the UK population), as well as other information from individuals and crime scenes.
As the large amount of DNA profiles which have been stored in NDNAD, "cold hits" may happen during the DNA matching, which means finding an unexpected match between an individual's DNA profile and an unsolved crime-scene DNA profile.
This can introduce a new suspect into the investigation, thus helping to solve the old cases.
CODIS is installed on each participated laboratory site and uses a standalone network known as Criminal Justice Information Systems Wide Area Network (CJIS WAN) The growing public approval of DNA databases has seen the creation and expansion of many states' own DNA databases.
California currently maintains the third largest DNA database in the world.
The most important function of the forensic database is to produce matches between the suspected individual and crime scene bio-markers, and then provides evidence to support criminal investigations, and also leads to identify potential suspects in the criminal investigation.
Interpol maintains an automated DNA database called DNA Gateway that contains DNA profiles submitted by member countries collected from crime scenes, missing persons, and unidentified bodies.
The DNA Gateway was established in 2002, and at the end of 2013, it had more than 140,000 DNA profiles from 69 member countries.
Unlike other DNA databases, DNA Gateway is only used for information sharing and comparison, it does not link a DNA profile to any individual, and the physical or psychological conditions of an individual are not included in the database.
Genealogical A national or forensic DNA database is not available for non-police purposes.